One thing I've noticed with the niacin is that you don't realize how much POIS really affects you until you don't have it.
I mean you know that it affects you, maybe you can put a quantitative value, but you see, once you are "POIS free", even though
it may be only temporarily, that it goes much beyond "quantitative".
It eats at your spirit, your sanity. Even if you can still function, in POIS, it's requires more energy and limits your effectivity.
For those who have had it since the beginning, they may not know what feeling healthy and alive really is.
I know that's a tough statement, but it's the reason we are working so hard to fix this thing!