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Hormonal Causes and Treatments / Re: Mast Cell Activation Syndrome
« Last post by Muon on April 04, 2025, 08:12:24 AM »Topical Lidocaine
https://www.reddit.com/r/POIS/comments/1jqagge/lidocaine_use_for_pois_symptom_relief/
”…overuse can even cause death”, per above reddit poster - Demo
Effect of lidocaine on histamine release and Ca2+ mobilization from mast cells and basophils
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-6576.1996.tb05577.x
***Forum Administrator (demografx) note:***
AI Overview
Lidocaine, while a useful local anesthetic, poses several hazards, including potential for allergic reactions, cardiovascular complications like arrhythmias and hypotension, and central nervous system effects like seizures and coma, especially with overdose or misuse.
https://www.reddit.com/r/POIS/comments/1jqagge/lidocaine_use_for_pois_symptom_relief/
”…overuse can even cause death”, per above reddit poster - Demo
Effect of lidocaine on histamine release and Ca2+ mobilization from mast cells and basophils
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-6576.1996.tb05577.x
Quote
Our results indicate that lidocaine directly inhibits histamine release from both rodent mast cells and human basophils
no great evidence that mast cells do or do not play a role in POIS - - demografx
***Forum Administrator (demografx) note:***
AI Overview
Lidocaine, while a useful local anesthetic, poses several hazards, including potential for allergic reactions, cardiovascular complications like arrhythmias and hypotension, and central nervous system effects like seizures and coma, especially with overdose or misuse.