Recent Posts

81

Poll Center / Re: Does smoking nicotine help?

« Last post by Warrior on November 11, 2024, 07:06:02 AM »

Hi, I?m wondering, since pois seems to be a sudden steep decline in dopamine, would smoking cigarettes help to raise that dopamine?

Maybe but boy would this be bad for your health long term. No luck with methyl donors / B vitamins?

82

POIS Research / Re: Google POIS Alerts

« Last post by demografx on November 10, 2024, 05:21:28 PM »

Google   
Post Orgasmic Illness Syndrome POIS
As-it-happens update
November 10, 2024
”Let’s Talk Sex” |               
Science Behind
Post Orgasmic Illness Syndrome:
Causes, Symptoms & Treatment
https://tinyurl.com/mpck6996
Written By :  Prof (Dr) Saransh Jain

83

Lifestyle Diary and POIS Summaries / Re: Progecitor's summary

« Last post by Progecitor on November 10, 2024, 11:06:49 AM »

By the way I ate about 10 pieces of Physalis in the morning and about two hours later the eye condition certainly improved. It didn’t do much else, but at least it shows that physalis has some clear benefit.

Hi Progecitor,

The research you are doing is awesome. I see you have tried physalis berries.

I have experimented with this berries a lot, trying different time frames and amounts.

The thing is the effect is barely noticeable, except if I use them in the exact right way, that I described in a post.
If they are used correctly, they prevent POIS from happening for me (it works only before orgasm). But if I miss the time frame, they have 0 effect.
In my opinion, that is why some people try them and think they are useless.

Some people tried them and have answered my post, saying that it worked 100% preventing POIS for them too.

Here is the link : https://poiscenter.com/forums/index.php?topic=3306.0

I think it's worth a try 

Keep me posted

I am sorry to hear that physalis stopped working for you and I hope you find something else soon.
Unfortunately I don’t think timing would change much in my case. To begin with I have chronic POIS and the symptoms are rather persistent. Thus when I have an O it does not initiate symptoms, but only makes them worse. It is true that there is a significant exacerbation in a short amount of time on such occasions. I have already found several good supplements that could ameliorate POIS to a great degree even at onset, however practically everything drops in efficacy very rapidly making them much less useful. I don’t think there were any occasions when POIS was completely prevented, but there were a few times when the supplements could greatly ameliorate the onset. Even so in the following days POIS would still emerge to some degree even though I would still take the supplements continuously.

84

Lifestyle Diary and POIS Summaries / Re: Progecitor's summary

« Last post by Muon on November 10, 2024, 10:46:35 AM »

Mast cells can be found in seminal fluid (in fertile men, infertile men or both?). I do not know what concentration is involved.

85

Poll Center / Does smoking nicotine help?

« Last post by quiteQuiet on November 10, 2024, 10:14:21 AM »

Hi, I?m wondering, since pois seems to be a sudden steep decline in dopamine, would smoking cigarettes help to raise that dopamine?

86

Lifestyle Diary and POIS Summaries / Re: Progecitor's summary

« Last post by Progecitor on November 10, 2024, 09:41:13 AM »

You may use the AI for a quick overview which staining/dyes highlight specific components of sperm. If I remember correctly Methylene blue might stain mast cells but some granules will show up with a different color than blue. The problem is that you do not have a reference of normal cell biology in general.

Do you think the mast cells are actually in the ejaculate?
Nevertheless I got some Methylene Blue some time ago and dropped some on the ejaculate sample when I last used the microscope. This turned out really funny as all the spermatozoa were swimming around with blue heads that was quite bizarre. Of course this is on top of doing microscopy on ones own sperm, which is quite bizarre as it is. Nevertheless I can’t say this lead to any new revelations and even if it has some problems my sperm appears mostly alright. I guess men with infertility issues must have even worse quality sperm and even so they probably don’t have POIS. As it was unlikely that doing microscopy would lead to any new information and because it is such a hassle, especially after an O I gave up on doing it a few months ago.

87

Lifestyle Diary and POIS Summaries / Re: Progecitor's summary

« Last post by Progecitor on November 10, 2024, 09:23:24 AM »

A microscope? Ideas on pois blod examing? https://poiscenter.com/forums/index.php?topic=4188.msg44773#msg44773


Pinhead sperm, a variation of the small-head sperm, is when the head appears as a pin with minimal to no paternal DNA content. The presence of pinhead sperm may point to a diabetic condition.

Sperm Morphology | Loma Linda University Center for Fertility ...

Thanks for this idea even if it is a bit late!
I gave up on microscopy some time ago as it was kind of a hassle and I couldn’t see the point after several occasions. There were some pin heads, but most of the time the majority seemed to have normal heads, thus the significance of these observations is questionable. An association to diabetes is probably an association to metabolic syndrome as well. Furthermore I think metabolic syndrome mostly equals lipid peroxidation as it means a generalized inflammation caused by excessive LPOs. Thus anyone with such a chronic inflammatory state probably has an altered sperm profile as well.
I was also considering to do some blood tests as you had mentioned, and wanted to take samples before and after an O. However when I decided to do so I simply couldn’t puncture myself. I tried to push the needle into one of the fingers, but it was not piercing and I grew so frustrated that I abandoned the idea. While I often get bloody scratches during work, I find it difficult to hurt myself voluntarily. It is also a problem that I have to work with my hands every day and such a wound can be painful for a week which makes grasping with it really annoying.

88

POIS Research / Re: POIS Theory Master List

« Last post by Muon on November 10, 2024, 06:50:08 AM »

An extension of the previous post:

No_Age1208:

EDIT 2: My hormones are all normal, which... fun. So wish that could've been a solution.

Good question from POIS patient:

Pois_sufferer:

So r u female, how do you react to periods ? Curious to know about it, as with all of us slight hormonal flush do mess with immune response that leads latent virus to Reactivation.

No_Age1208:

Definitely have a reaction to my periods, (flushing, joint pain) but not as severe as the kind I get to orgasms.

89

POIS Research / Re: POIS Theory Master List

« Last post by Muon on November 10, 2024, 06:16:55 AM »

https://www.reddit.com/r/POIS/comments/1gmfh78/comment/lwe6ke1/

Personally I believe this is all driven by the parasympathetic nervous system. Most of the people here fit the criteria of acetylcholine dominance. There are a few things you can do, but there is no magic pill. So your sympathetic system is asleep and your stuck in this dark state. The only way out is to lower choline. Choline manufactures acetylcholine, when acetylcholine is high dopamine is low. there is an inverse relationship to the two. Tonic water has quinine which lowers acetylcholine. Search reddit, loads of ideas on this. One way to tell is if your breath rate, is low like 8 breaths per minute. Normal is around 14 breaths per minute . Is your blood pressure low? All of these things show what's going on with the autonomic system.

https://poiscenter.com/forums/index.php?topic=3591.0

90

General Alternative Causes and Treatments of POIS / Re: Women with Post Orgasmic Illness Syndrome

« Last post by Muon on November 09, 2024, 01:19:24 PM »

An extension of the previous post:

No_Age1208:

EDIT 2: My hormones are all normal, which... fun. So wish that could've been a solution.

Good question from POIS patient:

Pois_sufferer:

So r u female, how do you react to periods ? Curious to know about it, as with all of us slight hormonal flush do mess with immune response that leads latent virus to Reactivation.

No_Age1208:

Definitely have a reaction to my periods, (flushing, joint pain) but not as severe as the kind I get to orgasms.