Post Orgasmic Illness Syndrome (P.O.I.S.)

General Category => Poll Center => Topic started by: Daveman on April 21, 2011, 11:07:18 AM

Title: Vitamin D levels
Post by: Daveman on April 21, 2011, 11:07:18 AM
CCconfusious had this doubt!

Interesting to take into consideration, at least conceptually, that summer sun has a lot to do with Vitamin D levels. Here in Chile we;re entering into fall, and I definitly feel the difference!

Title: Re: Vitamin D levels
Post by: Vandemolen on April 21, 2011, 05:08:52 PM
My Vitamin D level is 16. Should be at least 80. Had a special pill from the GP but that doesn't seem to work. So I booked 2 holidays for Asia and Africa. Enough sun and vitamin D.  :)
Title: Re: Vitamin D levels
Post by: hurray on April 22, 2011, 05:08:19 AM
I have spent the last year in a hot, sunny climate and my POIS symptoms have certainly become less problematic in that time period. There are many other variables concerning my POIS, but the vitamin D link is definitely an interesting one.
Title: Re: Vitamin D levels
Post by: Daveman on April 22, 2011, 09:47:47 AM
I have spent the last year in a hot, sunny climate and my POIS symptoms have certainly become less problematic in that time period. There are many other variables concerning my POIS, but the vitamin D link is definitely an interesting one.

We're coming upon fall here and I can guarrantee you that summer sun was a great releif to POIS!

Title: Re: Vitamin D levels
Post by: Ccconfucius on April 23, 2011, 10:26:14 AM
mine is 17ng/dl and should at least be 32 ng/dl, i was prompted to do mine becauseof vandemolen and guthrie's results.
what i was thinking is if i can bring up my vitamin D and loose weight, maybe i can reduce my recovery days.
vitamin d supposedly has something to do autoimmunity problems.
Title: Re: Vitamin D levels
Post by: sameer7777 on April 25, 2011, 08:17:13 PM
i dont know what is mibe vit D level is that important in POIS ..... so guide me how to know ......
thanks
Title: Re: Vitamin D levels
Post by: Daveman on April 26, 2011, 08:30:18 AM
sameer 7777

You can do a google search as follows below:
Copy the complete line below and paste it to the search window of Google.

Vitamin D POIS site:http://thenakedscientists.com/

There's a lot of information to be found there.

Vitamin D is by no means a cure, but maintaining decent levels can help reduce symptoms.

Title: Re: Vitamin D levels
Post by: Ccconfucius on April 26, 2011, 12:48:48 PM
sameer 7777

You can do a google search as follows below:
Copy the complete line below and paste it to the search window of Google.

Vitamin D POIS site:http://thenakedscientists.com/

There's a lot of information to be found there.

Vitamin D is by no means a cure, but maintaining decent levels can help reduce symptoms.



In addition to that you can go to your doctor to get test done or  if you are in america
you can go through websites like
prepaidlab.com to order a vitamind d test, go to local labcorp office and get blood drawn, this way you can avoid going to doctor and cost not to bad.
Lifeextension also does test.
or you can through zrt labs for home testing.

http://www.zrtlab.com/test-kits/blood-spot-testing-kits.html
http://www.lef.org/
prepaidlab.com
Title: Re: Vitamin D levels
Post by: Daveman on April 26, 2011, 01:11:01 PM
sameer 7777

You can do a google search as follows below:
Copy the complete line below and paste it to the search window of Google.

Vitamin D POIS site:http://thenakedscientists.com/

There's a lot of information to be found there.

Vitamin D is by no means a cure, but maintaining decent levels can help reduce symptoms.



In addition to that you can go to your doctor to get test done or  if you are in america
you can go through websites like
prepaidlab.com to order a vitamind d test, go to local labcorp office and get blood drawn, this way you can avoid going to doctor and cost not to bad.
Lifeextension also does test.
or you can through zrt labs for home testing.

http://www.zrtlab.com/test-kits/blood-spot-testing-kits.html
http://www.lef.org/
prepaidlab.com

Some of these sites and labs would be good information for the http://7.52.181.21/EMail_list.php database CC.
Title: Re: Vitamin D levels
Post by: Daveman on April 26, 2011, 01:42:46 PM
sameer 7777

You can do a google search as follows below:
Copy the complete line below and paste it to the search window of Google.

Vitamin D POIS site:http://thenakedscientists.com/

There's a lot of information to be found there.

Vitamin D is by no means a cure, but maintaining decent levels can help reduce symptoms.



In addition to that you can go to your doctor to get test done or  if you are in america
you can go through websites like
prepaidlab.com to order a vitamind d test, go to local labcorp office and get blood drawn, this way you can avoid going to doctor and cost not to bad.
Lifeextension also does test.
or you can through zrt labs for home testing.

http://www.zrtlab.com/test-kits/blood-spot-testing-kits.html
http://www.lef.org/
prepaidlab.com

Some of these sites and labs would be good information for the http://7.52.181.21/EMail_list.php database CC.
Also I have opened a thread (http://72.52.181.21/POIS/index.php?topic=71.0) for low cost testing and treatment methods.
Title: Re: Vitamin D levels
Post by: Samir on June 16, 2011, 10:09:22 AM
Interesting...I never thought about my vitamin D levels.  I take a multivitamin every day, but that may not be enough as there are times each week when I don't leave the house for DAYS.  But I do spend almost every Saturday all day in the sun, so maybe that makes up for it?
Title: Re: Vitamin D levels
Post by: UnderstandingPois on June 16, 2011, 03:22:14 PM
    i find it very depressing, that all my blood tests and organ checks are fine.    and it is not easy to get out and do all of this, i hope so much that they find something wrong with me but they never do and when i leave the doctors office i feel like crying, i walk home n see kids enjoying life and couples and people living their life and i am trying so hard evey single day for so many years just to be like them, just to feel human. it really sucks. im 20 yearsn old and in havent been able to live my life yet.
Title: Re: Vitamin D levels
Post by: Daveman on June 16, 2011, 05:53:03 PM
I know it doesn't help much, but this happens a lot with most rare disorders.

Title: Re: Vitamin D levels
Post by: Samir on June 16, 2011, 10:24:15 PM
    i find it very depressing, that all my blood tests and organ checks are fine.    and it is not easy to get out and do all of this, i hope so much that they find something wrong with me but they never do and when i leave the doctors office i feel like crying, i walk home n see kids enjoying life and couples and people living their life and i am trying so hard evey single day for so many years just to be like them, just to feel human. it really sucks. im 20 yearsn old and in havent been able to live my life yet.
A lot of times, you are your own best doctor.  $1000 worth of tests and doctors visits couldn't explain my neuropathy.  One day of changing to just eating salads showed me exactly what was wrong--I was diabetic.  Doctor's tests showed I was diabetic, but not enough to have neuropathy--well, I do and the tests never found it.
Title: Re: Vitamin D levels
Post by: UnderstandingPois on June 17, 2011, 02:24:16 AM
    yes, im done suffering, the only thing that has completely taken away my pois was medication, so im going to see a phyciatrist again, i dont care what happens, atleast i will feel better temporarly. i remember bieng on siezure medication and even that i felt great because i actually felt something other than pois. -nothing you know.

has anyone tried slow release melatonin, because people with pois complain that they don get refreshed sleep, and or they have insomnia. could be lacking proper rest and fatiguing our brain with arousil.

i took melatonin for 1 month and suddenly i felt really mad for no reason and my feelings and emotions started becoming stronger, coming back, ...................... i have trouble falling asleep and staying asleep, n i feel so worn out still when i wake up.

just some thoughts n ideas. 
Title: Re: Vitamin D levels
Post by: Habibou on June 17, 2011, 07:49:39 AM
    i find it very depressing, that all my blood tests and organ checks are fine.    and it is not easy to get out and do all of this, i hope so much that they find something wrong with me but they never do and when i leave the doctors office i feel like crying, i walk home n see kids enjoying life and couples and people living their life and i am trying so hard evey single day for so many years just to be like them, just to feel human. it really sucks. im 20 yearsn old and in havent been able to live my life yet.


Did you check your blood test in POIS or Out of POIS?

I always have an O the day before blood tests and it always underlline an important allergic reaction !
Title: Re: Vitamin D levels
Post by: sameer7777 on June 17, 2011, 07:57:25 AM
well melatonin didn't work for me , i couldn't sleep , yes pois really disturb my sleep .
i never get fresh wakeup in the morning ........
any way to sleep i take clonozepam 1 mg daily .........

i took zyrtec for my nostrils blockage and took 0.5 mg of clonozepam , it keeps me sleep for more , but never ever refresh wake ups ....
Title: Re: Vitamin D levels
Post by: Samir on June 17, 2011, 09:19:52 AM
Interesting, I forgot about the sleep issues.  I find that I need an extra hour to feel 85% as good as I normally would.  pois isn't allowing my body to repair things completely when I sleep.
Title: Re: Vitamin D levels
Post by: UnderstandingPois on June 17, 2011, 06:33:48 PM
yes i know, usually people with bad insomnia, will say that every hour you stay up life gets duller, you know and i feel like that all the time, i wake up and i dont feel like i even slept.
Title: Is the vitamin D many POISERs have, secondary ?
Post by: etcosp on May 28, 2021, 06:50:30 PM
I had a blood test a few days ago, which demonstrated I have a vitamin D deficiency.

Looking on this forum, I found tons of similar cases but couldn't find any clear answer about whether or not this deficiency is one of the main causes of POIS for the many who have it, or if we could identify a probable cause of POIS for those profiles.

If you know anything useful about it, please share it !

P.S. : I hope those askings have not been already posted. If yes, please redirect me :)
Title: Re: Is the vitamin D many POISERs have, secondary ?
Post by: Prospero on May 29, 2021, 04:11:49 AM
A lot of people in the world have Vit. D deficiency, it's extremely common, so it's difficult to show a correlation with Pois. Maybe it's an aggravating factor for Pois, maybe Vit. D is downregulated for some reason by the Poisers' bodies, maybe there isn't any link. Some Poisers have normal Vitamin D levels, others benefitted much from taking supplements, and it worsens the symptoms of another group of Poisers, while it did nothing for many. As for me it seems to decrease some symptoms and worsen others (importantly).
So I guess that there is no answer to your question.
Apart from "normal" Vitamin D, it could be interesting to test also for active Vitamin D (1.25 OH).
Title: Re: Vitamin D levels
Post by: berlin1984 on May 29, 2021, 03:44:19 PM
Also interesting if we'd have more data would be looking at VDR Bsm or VDR Taq mutations compared to "normal" people...
https://poiscenter.com/forums/index.php?topic=3694
Title: Re: Vitamin D levels
Post by: Hopeoneday on May 29, 2021, 04:19:26 PM
I think that i did go trought all genetic profiles of poisers
awailable and as i can remeber 99% if not 100%
hawe vitamine d vdr taq  mutation...
Title: Re: Vitamin D levels
Post by: Iwillbeatthis on May 30, 2021, 07:48:38 AM
"VDR Taq:  Vitamin D Receptor Taq Abnormality -Vitamin D has many functions, an issue because 90% of my patients have low or low normal Vitamin D levels.  Pertinent to this discussion, Vitamin D stimulate the enzymes that generate dopamine, a good reason to keep your Vitamin D level up, as we need dopamine to defend against microbes and metals, and to keep our mood up.  While we utilize SAMe (and indirectly other methyl group donors) to degrade dopamine, we also utilize methyl donors to generate dopamine.  Individuals with a normal Vitamin D receptor, those who are VDR Taq (-/-), make plenty of dopamine.  They tend not to need or to tolerate methyl groups or dopamine precursor substances.  With respect to methyl group need and tolerance, they behave like COMT (+) individuals.  Individuals (+/+) or (+/-) for VDR Taq defect have lower Vitamin D levels, make less dopamine, and will need and tolerate dopamine precursor substances and methyl donors.  With respect to methyl donor tolerance, VDR Taq (+) individuals behave like COMT (-) individuals.  All sorts of permutations are possible here, impacting on your tolerance and need for dopamine precursors and methyl groups.  I acknowledge that this is all very difficult to understand.  Hopefully the chart below will help."

COMT    (+/+) + VDR Taq (-/-)

Highest dopamine levels
Better tolerance to toxins and microbes
Low need tolerance for dopamine precursors and methyl donors
Greatest susceptibility to mood swings

In such as individual, we would utilize the “un methylated” forms of Methyl Cycle intermediates.  If an MTR/MTRR defect increases your need for methyl-B12, in this individual we would start with hydroxy-B12, to avoid ODing you with methyl groups, expecting that with enough hydroxy-B12 and free methyl groups floating around you will form up some methyl-B12, even if MTRR activity is compromised by a defect.  We would not give your dopamine precursors such as quercetin or the herb macuna puriens.  We would not advise a diet high in tyrosine, the amino acid precursor of dopamine.  COMT (+/+) VDR Taq (-/-) individuals will be susceptible to iodine and lithium depletion as they detoxify, and we will have to watch for this and supplement accordingly.

COMT    (-/-) + VDR Taq (+/+)

Lowest dopamine levels
Poor tolerance to toxins and microbes
Needs and tolerates dopamine precursors and methyl donors
Lowest susceptibility to mood swings

In such an individual, we would utilize the methylated forms of Methyl Cycle intermediates, including methyl-B12 if n TR/MTRR defect is present.  Dopamine precursors such as quercetin, ginkgo biloba, and the herb macuna puriens might be helpful, as would a diet high in tyrosine, the amino acid precursor to dopamine.  Other methyl donors, including melatonin, TMG, turmeric, theanine, along with MSM and SAMe (the latter two only for CBS (-/-) individuals) would make sense. To support BHMT, instead of Phosphatidylserine, we would use Pedi-Activ, which contains Phosphatidylserine and DMAE, a methyl donor.  Rather than using GABA to deal with excitotoxicity, we would use Zen, which combines GABA with the methyl donor threanine.

COMT (+/-) and VDR (-/-) behaves like COMT (+/+)
COMT (+/-) and VDR (+/+) behaves like COMT (-/-)

Multiple (+/-) combinations of COMT and VDR Taq are possible.  We will address these “intermediate” genotypes with intermediate levels of methyl group supplementation. 



COMT H62H  (+/+) Highest dopamine levels
COMT L136L (+/+) Lowest need for and tolerance to methyl group donors
COMT 61         (-/-) Greatest susceptibility to mood swings

COMT H62H  (-/-) Lowest dopamine levels
COMT L136L (-/-) Greatest need for and tolerance to methyl group donors
COMT 61       (+/+) Lower susceptibility to mood swings*


Both the COMT and VDR Taq status determine
need and ability to tolerate methyl donors. This chart goes from highest need for methyl donors to lowest need and ability to tolerate methyl donors.

COMT V158M/H62H-- VDR Taq++/TT need the most methyl donors
COMT V158M/H62H -- VDR Taq +-/Tt
COMT V158M/H62H -- VDR Taq --/tt
COMT V158M/H62H +-VDR Taq++/TT
COMT V158M/H62H +-VDR Taq +-/Tt
COMT V158M/H62H +-VDR Taq --/tt
COMT V158M/H62H ++VDR Taq++/TT
COMT V158M/H62H ++VDR Taq +-/Tt
COMT 61, V158M/H62H ++VDR Taq--/tt exquisitely sensitive to methyl donors