Post Orgasmic Illness Syndrome (P.O.I.S.)

POIS Cause/Treatment Discussions => Auto-Immune Causes and Treatments => Topic started by: dynamic on January 26, 2021, 07:04:47 AM

Title: Multiple scerosis and POIS
Post by: dynamic on January 26, 2021, 07:04:47 AM
Ok so I'm a bit concerned. I don't have POIS as nearly as bad as others. However, whenever I get sperm on my palms it causes a burning reaction and aching for a few days. My mum has MS which does put me at risk and so I feel like these two could be linked?
Title: Re: Multiple scerosis and POIS
Post by: Muon on January 27, 2021, 04:33:06 PM
Does your mother have an intravaginal sensitivity to semen? Like burning sensation upon contact? Mast cell mediators can induce demyelination, they sit right next to nerves. (MS is also a Th1 dominant condition if I'm not mistaken...I could be wrong). If your POIS is a type IV hypersensitivity or MCAS then it may put you at risk for MS. Diminished Th17 responses could also play a role. I suspect inflammation/weakness in my back/legs respectively are pseudo MS symptoms triggered by MC activation (heat, POIS).
Title: Re: Multiple scerosis and POIS
Post by: KWanchai70 on February 18, 2021, 04:42:10 AM
I also had sperm on my palm, it would cause a burning and pain reaction for a few days as well.
Title: Re: Multiple scerosis and POIS
Post by: Muon on July 20, 2021, 01:33:46 PM
https://www.tandfonline.com/doi/abs/10.1080/14728222.2020.1805435

"For the treatment of multiple sclerosis, NMDA antagonist, and sigma-1 receptor agonist eliprodil, has been shown to increase myelination 2-fold."