Post Orgasmic Illness Syndrome (P.O.I.S.)

General Category => Poll Center => Topic started by: Muon on December 15, 2020, 01:29:05 PM

Title: Next drug/med to test?
Post by: Muon on December 15, 2020, 01:29:05 PM
Temporary poll.
Title: Re: Next drug/med to test?
Post by: Iwillbeatthis on December 15, 2020, 03:54:44 PM
I would try pure epa oil also its cheap and you can take in combination while you're trying other treatments. I've finished a whole bottle of brain grain now and also a bottle of histaquel so two expensive flavonoid supplements neither helped my symptoms at all but everyone is different I guess.
My reactions to showers are improving from the epa oil and dysautonomia has also improved.
Title: Re: Next drug/med to test?
Post by: Vandemolen on December 15, 2020, 10:02:11 PM
I already tried oral cromolyn but it did not help me. I also tried Temazepam, which is a bit like diazepam. But that did not help me
Title: Re: Next drug/med to test?
Post by: Muon on December 16, 2020, 09:01:29 AM
A bit of reasoning behind it:

Nitroglycerine: Boosting dopamine via Nitric oxide
Neuroprotek: Long term use for mast cell stabilization or driving down cytokines in whole blood regardless of source.
Cromolyn: Modulating chloride currents in mast cells via GPR35 and/or calming down C-fibers in GI tract.
Profiling drug based on Dr. J. Goldstein's work: Probing for a neurosomatic disorder
Dexamethasone: People with elevated alarmin IL-33 may respond rapidly to dexamethasone the first time they try it.
Diazepam: Targeting adenosine A2B on mast cell for IL-8 and/or opioid receptors.
Title: Re: Next drug/med to test?
Post by: certainlypois2 on December 16, 2020, 10:07:35 PM
Dexamethasone: You will find out if it works the quickest.
I have also tried oral cromolyn, I didn't like the way I felt on it.
I will try it again though.