Post Orgasmic Illness Syndrome (P.O.I.S.)

POIS Cause/Treatment Discussions => Hormonal Causes and Treatments => Topic started by: Unvers on July 31, 2020, 07:23:01 AM

Title: Fluvoxamine
Post by: Unvers on July 31, 2020, 07:23:01 AM
https://en.wikipedia.org/wiki/Fluvoxamine (https://en.wikipedia.org/wiki/Fluvoxamine)

This antidepressant is the least known of the SSRI class, I have tried several of this class but he does not, it seems to me also helps from the cognitive point of view therefore it could be very useful against the cognitive symptoms of POIS in addition to the emotional ones, the sertraline instead I don't know if to recommend it because it seems to me that it antagonizes a sigma receptor and consequently even if from an emotional point of view it helps causes a slight cognitive dysfunction which when it is in POIS can be very annoying.
Title: Re: Fluvoxamine
Post by: Muon on July 19, 2021, 11:52:10 AM
Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain (https://sci-hub.se/https://www.sciencedirect.com/science/article/abs/pii/0014299996002543?via%3Dihub)

https://en.wikipedia.org/wiki/Sigma_receptor#Ligands

https://poiscenter.com/forums/index.php?topic=3669.msg41576#msg41576