Post Orgasmic Illness Syndrome (P.O.I.S.)

General Category => What is POIS => Topic started by: Outsider on July 03, 2015, 09:04:32 PM

Title: The pois is over
Post by: Outsider on July 03, 2015, 09:04:32 PM
Today the 3 july 2015 it was my birthday
i couldn't expect so huge present for my now 37 years

A long, long way so much sacrifices and finally i beat the illness
in 2012 my pois almost killed me
i was in the hospital, i stayed 5 days in a bed like dead
the doctors didn't know was wrong, so they put me in psychiatric section and refusing to study my case
a strange feeling to feel the death
i hadn't the time to cry
at this moment it was the beginning of my study
i wrote three books, with notes, theory
i bought a smartphone beacause of that
for writing my treatments, the effects, the changements, the results, be aware and make my research
i printed hundreds medicals files, read hundreds articles, you know this story
i had to stop my work, i was photographer, too sick
i had to stop seeing my friends, and i lost amost all of them
i saw rarely my familly
for 4 years i was living like that.
It wasn't living but just surviving
my only focus was the pois
i had only that, beat that sickness
and go back to a normal life
i have no wife, no children
and i couldn't
Finally i done what i have to do
Now i feel like a normal guy
i had strong physicals, psycho, and neuro symptoms
now it s over.
I ll reply you in a few days
my study.
It was not only my victory but our victory
the doctors, hospitals, refused to do their job
so we did it
we beat and finish a rarely sickness
i don't know if there s any case like that in history

Demo, i never found the moment to speak with you
i just want to say thank you for all you did for the communauty
you probably saved my life with this website and for others poisers
the same for you daveman
steph thanks for your kind messages, your support, i did it !!
quantum, je voulais te remercier aussi pour tes messages, ton devouement, ta motivation et ta presence active sur le forum
si tu veux on pourra se parler via skype
labyrinth we shared so much messages, you know, you were so much busy on the forum
i hope my study ll cured you
thanks all the others poisers on the forum

i ll write in a couples of days
my study
there s hopê
there have always been hope
outsider

Title: Re: The pois is over
Post by: demografx on July 04, 2015, 03:00:45 PM
(http://sl.glitter-graphics.net/pub/443/443043g3rcicluog.gif)

Outsider!


Title: Re: The pois is over
Post by: Labyrinth on July 04, 2015, 04:07:45 PM
what is happening brother ?! any thing extraordinary
Title: Re: The pois is over
Post by: Stef on July 04, 2015, 07:37:43 PM
Outsider,

It sounds like something very good has happened for you!

We're looking forward to hearing all about it.

Stef
Title: Re: The pois is over
Post by: Jimmy on July 05, 2015, 11:41:39 AM
Happy to hear about your success !

Can't wait to know the details ...
Title: Re: The pois is over
Post by: Jimmy on July 10, 2015, 09:38:53 AM
Will you provide updates outsider ?

Thanks,
Title: Re: The pois is over
Post by: FloppyBanana on July 10, 2015, 01:34:47 PM
yep...
Title: Re: The pois is over
Post by: Outsider on July 10, 2015, 03:56:08 PM
the research is right something is wrong with the vagus nerve
it seems like there s a inflammation on the left side on the x nerve
who can be explained by the shower problem
this Dysfunction, decrease the level of acethylcholine.

my addiction to olanzapine
helped to understand better my pois.
I tried so many times to stop it, or to switch it with many complement food and medication
i always failed.
So i remembered something
olanzapine decrease the level of dopamine, noradrenaline, and  adrenalin.
So it s like many neuroleptic a cholinergic effect, who increase the vagal activity
high nora, adrena, and dopa= low vagal activity.
Theses hormones are released with  Excitement
like our pois.
For me, sexe without ejaculation is enough for being sick because of the excitement
the nicotine, coffee, tea are also involved with Excitement.

for the shower, if i pass hot water on the left side on my neck
i m pretty bad sick, with strong inflammatory symptoms
but if i miss this part of the body and pass a few minutes on the right side of the vagus nerve
i m not sick and it really help me.
But not too long and too hot.
on the other hand, cold on the left side of the vgs nrve, decrease the symptoms.


With my olanzapine study,
i stopped it and tried a cholinergic
the mytelase,
and soy Lecithin for keeping high level of choline
and acethylcholine.
The mytelase  helps for ach the transmission  and increases levels of ach.
When i began this medication, i was like cured
the neuro and psycho symptoms were gone, and it was just wonderfull to feel any symptoms.

The mytelase has stong side effect
tough spasms, nausea, dizziness
i take it at the end of my meal
and it s perfect.
I take 60mg by day
i tried 30mg it doesn't work.

I  hope it ll help you.
Reply me in this link if you try the treatment
and tell me  the results
this is perhaps the beginning of something
Title: Re: The pois is over
Post by: Colm on July 11, 2015, 02:15:30 PM
Hi Outsider,

Congratulations on getting a cure for your POIS and relief from your symptoms.

I am just curious, do you think this is the final fix for your symptoms?

If so, it would be great if you can explain this a little more.

Most of the things you mention seem like drugs that a person would need to get on a prescription from their GP.

Also, are there also potential side effects here to be considered?

As you seem confident that this is a potential identification of the causes of POIS and potential solution, based on what seems like severe symptoms and also a lot of analysis and pain staking research from you, I hope the researchers are looking at this idea and your contributions.

Hope it is good news and a final result for you.

A final question - do you think this approach is most likely to work best if a person has not suffered from POIS for too long.

My own theory is that the longer one had experienced the chronic symptoms of POIS, the harder it is to shift. It is my experience but may not be true. As ever, I am really interested in everyone's opinions as I learn a lot from reading the forum posts.
Title: Re: The pois is over
Post by: demografx on July 11, 2015, 11:47:18 PM

My own theory is that the longer one had experienced the chronic symptoms of POIS, the harder it is to shift.


Colm, I used to think the same way...until I found my personal silver bullet...after 30++ years of severe POIS -- and numerous failures.

No in-depth theories/analytics: I think I just got very lucky.
Title: Re: The pois is over
Post by: Outsider on July 12, 2015, 06:27:47 AM
Hi Outsider,

Congratulations on getting a cure for your POIS and relief from your symptoms.

I am just curious, do you think this is the final fix for your symptoms?

If so, it would be great if you can explain this a little more.

Most of the things you mention seem like drugs that a person would need to get on a prescription from their GP.

Also, are there also potential side effects here to be considered?

As you seem confident that this is a potential identification of the causes of POIS and potential solution, based on what seems like severe symptoms and also a lot of analysis and pain staking research from you, I hope the researchers are looking at this idea and your contributions.

Hope it is good news and a final result for you.

A final question - do you think this approach is most likely to work best if a person has not suffered from POIS for too long.

My own theory is that the longer one had experienced the chronic symptoms of POIS, the harder it is to shift. It is my experience but may not be true. As ever, I am really interested in everyone's opinions as I learn a lot from reading the forum posts.


Hi colm,
this treatment isn't psychotropic
Lecithin soya is a complement food
and mytelase is neuro meds

Also, to pass hot or cold in the vagus nerve like i explained
works pretty good

Now i m taking mytelase at the end of my meal, and i don't have the side effect
if i had to choose between the side effect of mytelase and my pois
i take the first option .....

Now, i m like you, i had my pois for a long time, since 14 years old, and i m 37 years old now
my symptoms were getting too strong

i advise you to adapt this study to your own pois
the same for the others
reply me in this link

 
Title: Re: The pois is over
Post by: Ccconfucius on July 12, 2015, 04:00:29 PM
outsider thanks for the post and  effort


How long did you try this solution before seeing improvements, does work almost right away or do you have to wait for the effects to build. 
When  running water across the vagus nerve,  how hot is the water and cold is the water
Why does hot water and cold water affect the vagus nerve differently
From your research what is connection between vagus nerve and acetylcholine
Why is increasing  choline intake not enough to provide relief

" some personal somewhat proof for this solution":  from my little reading after seeing your post i discovered an abundance of the neurotransmitter acetylcholine, combined with a nearly complete absence of monoamine - neurotransmitters histamine, serotonin, and norepinepherine promotes Rem sleep, which is when  dreams are most vivid. I have  known for a long time that my dreams are not as vivid and " creatively weird" when am in pois compared to when am normal.
https://en.wikipedia.org/wiki/Rapid_eye_movement_sleep


Title: Re: The pois is over
Post by: Starsky on July 12, 2015, 04:00:55 PM
Did you try lighter remedies for rising Acetyloholine? Huperzine A or Acetyl-l-carnitine?
Title: Re: The pois is over
Post by: fidalgo on July 13, 2015, 01:13:22 PM
I always thought that our problem must be high level of acetilcholine (http://mindrenewal.us/page13.html) but not low. High level of acetilcholine would explain the vivid dream almost all of poisers have.

But it is very interesting that this helps you, outsider. Answer to me: do you also have vivid dreams when you are in POIS?

One doubt: exist a exam to detect the lever of acetilcholine in our body?
Title: Re: The pois is over
Post by: Labyrinth on July 13, 2015, 08:03:34 PM
for me anything that raises acetyl choline hurts me so . there is interpersonal variations and we dont have the exact same illness . we have different pathology with the same manifestation . i tried soy lecithen before and put me on brain fire . thanks outsider good job hope u have better life now
Title: Re: The pois is over
Post by: Outsider on July 15, 2015, 06:56:28 AM
outsider thanks for the post and  effort


How long did you try this solution before seeing improvements, does work almost right away or do you have to wait for the effects to build. 
When  running water across the vagus nerve,  how hot is the water and cold is the water
Why does hot water and cold water affect the vagus nerve differently
From your research what is connection between vagus nerve and acetylcholine
Why is increasing  choline intake not enough to provide relief

" some personal somewhat proof for this solution":  from my little reading after seeing your post i discovered an abundance of the neurotransmitter acetylcholine, combined with a nearly complete absence of monoamine - neurotransmitters histamine, serotonin, and norepinepherine promotes Rem sleep, which is when  dreams are most vivid. I have  known for a long time that my dreams are not as vivid and " creatively weird" when am in pois compared to when am normal.
https://en.wikipedia.org/wiki/Rapid_eye_movement_sleep


Cold is anti inflammatory
Hot is relaxing, but inflammatory
That s why shower can help some poisers
Or make you sick.
And it s affecting the x nerve for the bad or the good.
You need to experiment by youself and adapting for your own Pois.
The mytelase works in 30mn and live 5h, 6h.
For me completly cured the same Day, and i can feel the inprovement in 1h.
It s important to take it with food, at the end of your meal.

The acetylcholine is made by the vagus nerve.
I know it s not easy but you need to adapt all this informations with your own pois.
Especially if you have another medication like neuroleptics and anti histaminic
Title: Re: The pois is over
Post by: fidalgo on July 15, 2015, 03:24:05 PM
Outsider,
 How much is  mytelase in your country? Does it need prescription?

I loof for it in Brazil, but it is not produced here....
Title: Re: The pois is over
Post by: Outsider on July 15, 2015, 03:42:39 PM
Outsider,
 How much is  mytelase in your country? Does it need prescription?

I loof for it in Brazil, but it is not produced here....

Hi fidalgo,
i don't know about the price, i have my insurance in france.
But i don't think so it s an expensive stuff
there s other medication who work like mytelase.
Looking for, cholinergic treatment, helping for transmission nerve and acetylcholine.
You need to make some research and to ask your doctor, especially if you already have a treatment.
You know, it s better to speak with your doctor about this study, and if he s ok for a prescription with these neuro meds.

For me it s safe, i made some long research, before, and it s fucking work
 know, i m taking mytelase with food i don t have the side effect anymore.

Reply us, if you have the opportunity to try this neuro meds.
And also, think about acetylcholine level
take care with food, and don t forget to take it a the end of the meal

Hoping, it ll help you
Title: Re: The pois is over
Post by: FloppyBanana on July 19, 2015, 10:20:49 AM
Hi Oursider,

I am glad you have found something that works. Have you worked out the most you can shoot in a month yet? For me with my medication the "happy" balance is having sex 3 times a month. This means I can give her max 12 orgasms a month (usually 3 weekends in bed). This is because I can pleasure her orally without getting POIS when I take progesterone. I does mean the window of opportunity is quite small and sex for her can only happen on nine specific days of the month. I recently broke my ten day shoot rule and was fine until 6 days later when I found myself in complete exhaustion and a two day depression (crying like a baby). Just thought I would share that! One good side effect of taking progesterone is that it reduces sex drive. I very rarely wake up with a raging hard on now so it has a little effect on reducing sexual frustration. I think we know what sexual frustration feels like!

Can you please clarify the following points:

1) How long have you been trailing mytelase?
2) How do you take the medication? (for example after one orgasm I take 35mg of progesterone over five days to minimise symptoms. Thats daily amounts if 10,10,5,5,5mg respectively)
3) do you take the drug as and when required or all the time?
4) How long does it take to work? (e.g. for me I know progesterone fully kicks in after 30 mins)

I look forward to your response!

Thanks FloppyB
p.s. I saw that mytelase has a low bioavailablilty. I wonder if that means that there is more chance of getting an inconsistent dose as only a low amount is absorbed by the body...
Title: Re: The pois is over
Post by: FloppyBanana on July 25, 2015, 12:32:49 PM
Hi Outsider,

I'm looking forward to hearing your response to my questions in this trail:-)  I went to a local GP in the UK where I live and asked for Mytelase. He advised that it would not be possible to get it from a GP on the national health service. I mentioned you got it from a GP in France. The UK GP advised me I could go to France and probably be able to get it. He also mentioned trying to see a specialist, which I am, a neurologist.

Also, I'm curious how many times a day you take it. Is the 60mg spread across a few meals?

Thanks!!!!!! FloppyB
Title: Re: The pois is over
Post by: Outsider on July 28, 2015, 02:16:47 PM
Hi Oursider,

I am glad you have found something that works. Have you worked out the most you can shoot in a month yet? For me with my medication the "happy" balance is having sex 3 times a month. This means I can give her max 12 orgasms a month (usually 3 weekends in bed). This is because I can pleasure her orally without getting POIS when I take progesterone. I does mean the window of opportunity is quite small and sex for her can only happen on nine specific days of the month. I recently broke my ten day shoot rule and was fine until 6 days later when I found myself in complete exhaustion and a two day depression (crying like a baby). Just thought I would share that! One good side effect of taking progesterone is that it reduces sex drive. I very rarely wake up with a raging hard on now so it has a little effect on reducing sexual frustration. I think we know what sexual frustration feels like!

Can you please clarify the following points:

1) How long have you been trailing mytelase?
2) How do you take the medication? (for example after one orgasm I take 35mg of progesterone over five days to minimise symptoms. Thats daily amounts if 10,10,5,5,5mg respectively)
3) do you take the drug as and when required or all the time?
4) How long does it take to work? (e.g. for me I know progesterone fully kicks in after 30 mins)

I look forward to your response!

Thanks FloppyB
p.s. I saw that mytelase has a low bioavailablilty. I wonder if that means that there is more chance of getting an inconsistent dose as only a low amount is absorbed by the body...



Hi floppy, all,

i began lecithine soya the 19/06
2, 4, 6 or 7 per day

30/06
mytelase

the 19/06 to 29/06
3 orgasms
some good result with lecithin soya
but not always

the 30/06-07/07
mytelase mixed with lecithine soya
my usual treatments cetirizine and citalopram
free olanzapine when i began this new treatment

2 orgasms
2x20 at 3x20mg mytelase by day
6 or 8 lecithin per day
20mg the morning, 20mg the afternoon and 20mg the night (mytelase)
without food and strong side effect

completly free neuro and psycho symp
physical symp very low

08/07-14/07
mytelase
0mg at 2x20mg by day
with food and no side effect
lecithine soya 6, 7 per day
10mg olanzapine one day

4 orgasms
symp sometimes reappear
some days free neuro, psycho symp
physical smp low


15/07-21/07
2 orgasms
olanzapine 5mg per day
after Orgasm 10mg olanzapine
the next days 5 mg olanzapine
mytelase
3x20mg after the Breakfast, launch and diner
2, 4 lecithine soya

symp more tough
serious improvement the second day after orgasm
with mytelase and lecithin soya

21/07-28/07
3 orgasms
still 5mg olanzapine
3x20, or 4x20mg mytelase
6, 8 lecithin soya

the symp are there the next day after orgasm
but very low the second day after taking 40mg mytelase and lecithin

i take the mytelase and lecithin everyday
the morning, after lunch and dinner
the mytelase alone doesn't work
the same for lecithin soya
it seems like they work together

i take mytelase first and 1, 2 hours after 2 lecithin
and in 30mn, 1 hour  the symp are low
it works 5h at 7h,

Acetylcholinesterase inhibitor
mytelase=Ambénonium Chlorure
MESTINON=Pyridostigmine bromure
PROSTIGMINE =Néostigmine méthylsulfate

ASk YOUR DOCTOR BEFORE TRYING THEM

Hoping it ll help you

 








Title: Re: The pois is over
Post by: FloppyBanana on August 22, 2015, 05:15:08 AM
Meytelase may be difficult to get in the US. See below link:

http://neuroforbundet.se/PageFiles/20450/FDA%20and%20the%20MG%20Foundation%20of%20America%20-%20Mytelase%202012%2012%2017.pdf
Title: Re: The pois is over
Post by: Ccconfucius on August 27, 2015, 01:14:34 PM
Meytelase may be difficult to get in the US. See below link:

http://neuroforbundet.se/PageFiles/20450/FDA%20and%20the%20MG%20Foundation%20of%20America%20-%20Mytelase%202012%2012%2017.pdf

there are other cholinesterase inhibitors, prescribed in the US. They are mostly used for Alzheimer patients. One of them is donepezil, which according to Wikipedia  has a good bioavailibility,crosses the blood brain barrier and has long half life.
Title: Re: The pois is over
Post by: VSmasher on August 27, 2015, 01:43:32 PM
My problem is too much acytlecholine after orgasm. When I take an Anti-Acetyloholine drug (tianeptine) after sex , my symptoms go away.
Title: Re: The pois is over
Post by: b_jim on August 27, 2015, 03:03:07 PM
Hmm,  tianeptine as anti-acethyl-choline med?
Wikipedia says tianeptine is a pro-dopaminergic med like amineptine.

Anyway it could be 1 more element for dopamine theory.
Title: Re: The pois is over
Post by: demografx on August 27, 2015, 04:29:41 PM
Hmm,  tianeptine as anti-acethyl-choline med?
Wikipedia says tianeptine is a pro-dopaminergic med like amineptine.

Anyway it could be 1 more element for dopamine theory.

b_jim, re dopamine: my psychiatrist told me (a few years ago) that if dopamine was responsible for POIS then cocaine might work -- but that's  a very dangerous approach!

Interesting thought.

But he (or I) do NOT recommend this.


Title: Re: The pois is over
Post by: b_jim on August 28, 2015, 01:21:09 AM
Hmm,  tianeptine as anti-acethyl-choline med?
Wikipedia says tianeptine is a pro-dopaminergic med like amineptine.

Anyway it could be 1 more element for dopamine theory.

b_jim, re dopamine: my psychiatrist told me (a few years ago) that if dopamine was responsible for POIS then cocaine might work -- but that's  a very dangerous approach!

Interesting thought.

But he (or I) do NOT recommend this.

Absolutely !
I remember a doctor asking me if I take drugs or alcohol.
I answer no but I really think cocaine must cure my Pois. But this drug is impossible to take without danger because too much addictive. We are here to find a cure. That does not make sense to take an easy way leading to the death.
Title: Re: The pois is over
Post by: demografx on August 29, 2015, 01:06:22 AM
Hmm,  tianeptine as anti-acethyl-choline med?
Wikipedia says tianeptine is a pro-dopaminergic med like amineptine.

Anyway it could be 1 more element for dopamine theory.

b_jim, re dopamine: my psychiatrist told me (a few years ago) that if dopamine was responsible for POIS then cocaine might work -- but that's  a very dangerous approach!

Interesting thought.

But he (or I) do NOT recommend this.

Absolutely !
I remember a doctor asking me if I take drugs or alcohol.
I answer no but I really think cocaine must cure my Pois. But this drug is impossible to take without danger because too much addictive. We are here to find a cure. That does not make sense to take an easy way leading to the death.

Death.

Exactly. also...

Jail.

It is illegal in almost all countries.
Title: Re: The pois is over
Post by: Outsider on August 31, 2015, 11:51:16 AM
Hmm,  tianeptine as anti-acethyl-choline med?
Wikipedia says tianeptine is a pro-dopaminergic med like amineptine.

Anyway it could be 1 more element for dopamine theory.

b_jim, re dopamine: my psychiatrist told me (a few years ago) that if dopamine was responsible for POIS then cocaine might work -- but that's  a very dangerous approach!

Interesting thought.

But he (or I) do NOT recommend this.

Absolutely !
I remember a doctor asking me if I take drugs or alcohol.
I answer no but I really think cocaine must cure my Pois. But this drug is impossible to take without danger because too much addictive. We are here to find a cure. That does not make sense to take an easy way leading to the death.

Death.

Exactly. also...

Jail.

It is illegal in almost all countries.

Exactly demo
I thought a couple of times
TO try cocaine
It decrease vagus nerve activity
And increase adrenaline, noradrénaline and perhaps dopamine
As you said, it s a powerfull drug,
This is not safe.
Is there any one who tried zyban
An anti pressant who increase
Dopa and adre ?
I wanted but too expansive in France
Title: Re: The pois is over
Post by: fidalgo on August 31, 2015, 02:47:58 PM
My problem is too much acytlecholine after orgasm. When I take an Anti-Acetyloholine drug (tianeptine) after sex , my symptoms go away.

I believe I fave high acetylcholine, but I read that tianeptine is not a anti-acetylcholine.

Tianepetine help in 100% in your POIS?

I read that has a lot of anticholinergic meds. Does anyone have improves with some of them?
Title: Re: The pois is over
Post by: Mr Raba on November 22, 2015, 03:29:46 PM
Trying pure encapsulations alpha-GPC  an advanced delivery form for phosphatidylcholine to increase acethylcholine.   It is a big help in 3 non POIS days so far.  I am in my fourth day. And day 1 after O.

I also take immunocal which is a very special whey protein which affects neurotransmitters and a powerful antioxidant. I is also a powerful lactic acid scavenger.  It  gives me lots of energy.  Can get that at amazon.com  about $80 for 30 packs (a month supply for me)

My mind is so much clearer and anxiety is almost gone with the combo.  Immunocal alone helps (taken it since 2000), but the mental clarity and peace comes from the phosphatidylcholine. Immunocal tends to increase inflammation some...

Today is day one after O.   Much, much better.  The social anxiety, concentration, inability to deal with stressful situations is almost gone!   I need to take about 3 pills a day spaced out  to keep levels up throughout the day. Still tired some, but so much better.  The feeling that the brain is on fire (I believe due to inflammation) is mostly gone.    I feel so much better and I am very optimistic about our future.  I feel the phospholipid layer in our cells  may be compromised, which limits energy production in the cells and inter cellular interactions. This may also be affecting neurological communications.

I believe that as I continue to use it everyday my body will slowly recover completely in time.  The alpha-GPC has made a phenomenal difference in just 4 days.  I buy it from www.purecaps.com.   

It is pricy, but sign up a "health practitioner" and they give a 50% discount if you sign up as such.  So it is about $20 bucks for 60 caps.
You might want to save money that way too.  Heck I practiced on my self for 23 years!  LOL

I will also try phosphatidylserine which also increases acethylcholine and see what happens.

____________

POIS and CFS sudden  simultaneous onset since 1993.
Title: Re: The pois is over
Post by: Quantum on November 24, 2015, 09:40:55 AM
Trying pure encapsulations alpha-GPC  an advanced delivery form for phosphatidylcholine to increase acethylcholine.   It is a big help in 3 non POIS days so far.  I am in my fourth day. And day 1 after O.

...

My mind is so much clearer and anxiety is almost gone with the combo.  Immunocal alone helps (taken it since 2000), but the mental clarity and peace comes from the phosphatidylcholine. Immunocal tends to increase inflammation some...

...
It is pricy, but sign up a "health practitioner" and they give a 50% discount if you sign up as such.  So it is about $20 bucks for 60 caps.
You might want to save money that way too.  Heck I practiced on my self for 23 years!  LOL

I will also try phosphatidylserine which also increases acethylcholine and see what happens.


Hi Mrraba,

I am glad for you that you have found some relief for your POIS symptoms.

Before trying this expensive brand of phosphatidylcholine, did you try the common and much cheaper lecithin capsules ? They are a natural source of phosphatidylcholine, phosphatidylserine, as well as of other phospholipids ( https://en.wikipedia.org/wiki/Lecithin ). 

I always keep an eye on the cost-effectiveness ratio of treatment options.

Title: Re: The pois is over
Post by: joelawerence on January 28, 2016, 08:18:19 AM
Hi Outside, Does this treatment still work for you? Also, have you tried taking Magnesium supplements before and if so was it effective?
Title: Re: The pois is over
Post by: Nas on March 21, 2016, 01:43:39 PM
I bought a food supplement that contains Lecithin and vitamin D3 and I couldn't find Mytelase but my doctor prescribed Memantine hope they will show any effects, will inform you if it works.
Title: Re: The pois is over
Post by: demografx on March 21, 2016, 08:40:54 PM
Nas, welcome to the forum :)
Title: Re: The pois is over
Post by: Quantum on March 22, 2016, 07:47:33 AM
I bought a food supplement that contains Lecithin and vitamin D3 and I couldn't find Mytelase but my doctor prescribed Memantine hope they will show any effects, will inform you if it works.

It will be interesting to hear about the results you get.

I suppose you have cognitive symptoms, and/or muscles symptoms? 

Memantine is a NMDA receptor blocker.  I have benefit from less potent NMDA receptors blockers, like magnesium, flaxseed oil ( lignam), L-Theanine, zinc, and the like.  I have recently found that rosmarinic acid, that I have been using for years for POIS relief through rosemary extract, has acetylcholinesterase properties ( in addition to its gabaergic properties and its IDO inhibitor properties).
 
Memantine seems to have an affinity for brain tissue, so it is used in Alzeimer disease.  But Memantine has effect on other neurotransmitters.  It also is, among other thing, a dopaminergic agonist.  More potency and a broader range of action means it has more potential for side effects, though. 

Is there any reason your doctor have chosen to go with another class of drug than Mytelase, which is a cholinesterase inhibitor?  He could have chosen another cholinesterase inhibitor, like donezepil or galantamine.

Title: Re: The pois is over
Post by: Nas on March 22, 2016, 01:28:31 PM
Nas, welcome to the forum :)
Thanks bro.
Title: Re: The pois is over
Post by: Nas on March 22, 2016, 01:44:38 PM
I bought a food supplement that contains Lecithin and vitamin D3 and I couldn't find Mytelase but my doctor prescribed Memantine hope they will show any effects, will inform you if it works.

It will be interesting to hear about the results you get.

I suppose you have cognitive symptoms, and/or muscles symptoms? 

Memantine is a NMDA receptor blocker.  I have benefit from less potent NMDA receptors blockers, like magnesium, flaxseed oil ( lignam), L-Theanine, zinc, and the like.  I have recently found that rosmarinic acid, that I have been using for years for POIS relief through rosemary extract, has acetylcholinesterase properties ( in addition to its gabaergic properties and its IDO inhibitor properties).
 
Memantine seems to have an affinity for brain tissue, so it is used in Alzeimer disease.  But Memantine has effect on other neurotransmitters.  It also is, among other thing, a dopaminergic agonist.  More potency and a broader range of action means it has more potential for side effects, though. 

Is there any reason your doctor have chosen to go with another class of drug than Mytelase, which is a cholinesterase inhibitor?  He could have chosen another cholinesterase inhibitor, like donezepil or galantamine.

Yeah, I mostly have Psychological symptoms, the physical symptoms are merely feeling suddenly cold or hot and sometimes flu like symptoms but too weak. I don't really know about the memantine though my doctor gave me only 5mg in the morning which after I took couldn't notice any difference and I'm pretty hesitant to masturbate in fear of the medications being not effective and screw my self up.
I really don't know though why did he choose an NDMA inhibitor, I even showed him the mytelase and some other Acetylcholinesetrase inhibitors but he told me that they don't have them.
My psychological symptoms are heavy and plenty starting from anxiety to total brain fog, social disconnection, problem with words and loss of motivation.
Do you think having an orgasm is a good idea after not noticing any effects from the medication ?
Title: Re: The pois is over
Post by: Nas on March 22, 2016, 08:56:40 PM
I bought a food supplement that contains Lecithin and vitamin D3 and I couldn't find Mytelase but my doctor prescribed Memantine hope they will show any effects, will inform you if it works.

It will be interesting to hear about the results you get.

I suppose you have cognitive symptoms, and/or muscles symptoms? 

Memantine is a NMDA receptor blocker.  I have benefit from less potent NMDA receptors blockers, like magnesium, flaxseed oil ( lignam), L-Theanine, zinc, and the like.  I have recently found that rosmarinic acid, that I have been using for years for POIS relief through rosemary extract, has acetylcholinesterase properties ( in addition to its gabaergic properties and its IDO inhibitor properties).
 
Memantine seems to have an affinity for brain tissue, so it is used in Alzeimer disease.  But Memantine has effect on other neurotransmitters.  It also is, among other thing, a dopaminergic agonist.  More potency and a broader range of action means it has more potential for side effects, though. 

Is there any reason your doctor have chosen to go with another class of drug than Mytelase, which is a cholinesterase inhibitor?  He could have chosen another cholinesterase inhibitor, like donezepil or galantamine.

Ok, so never mind, I did masturbate two times and I feel like crap, didn't notice any effects psychologically maybe physically it was effective but still having the same depression, lack of motivation, anhedonia, problem with words, anxiety, etc..
Any advice ? would be really helpful and yes I do take anti-depressants but they only make me less depressed
Title: Re: The pois is over
Post by: Quantum on March 23, 2016, 07:24:28 PM
Ok, so never mind, I did masturbate two times and I feel like crap, didn't notice any effects psychologically maybe physically it was effective but still having the same depression, lack of motivation, anhedonia, problem with words, anxiety, etc..
Any advice ? would be really helpful and yes I do take anti-depressants but they only make me less depressed

Hi Nas,

We cannot give medical advice here on the forum.  However, we can share what works for us.  So you can read on the forum about what works for others.  If something seems interesting for you to try, you then check with a health professional if it is o.k. for you, considering your conditions and the medication you are taking.  In any case, for supplements, always use safe doses, starting very low, and try only one new thing at a time.

If you want to read what is safe for me and works for me, see the first post in this thread (http://poiscenter.com/forums/index.php?topic=2090.msg16604#msg 16604)

 
Title: Re: The pois is over
Post by: Nas on March 23, 2016, 08:58:34 PM
Ok, so never mind, I did masturbate two times and I feel like crap, didn't notice any effects psychologically maybe physically it was effective but still having the same depression, lack of motivation, anhedonia, problem with words, anxiety, etc..
Any advice ? would be really helpful and yes I do take anti-depressants but they only make me less depressed

Hi Nas,

We cannot give medical advice here on the forum.  However, we can share what works for us.  So you can read on the forum about what works for others.  If something seems interesting for you to try, you then check with a health professional if it is o.k. for you, considering your conditions and the medication you are taking.  In any case, for supplements, always use safe doses, starting very low, and try only one new thing at a time.

If you want to read what is safe for me and works for me, see the first post in this thread (http://poiscenter.com/forums/index.php?topic=2090.msg16604#msg 16604)

yeah I've checked your forum and hell you take alot of medications, for me I will try some real acetylcholinesetrase inhabitors and see if they work
god this illness is a serious curse. I mean, sex is one of the most enjoyable things in life and my self is a loner so I have a lot of time with my self and for me it has been always the choise between real life, or masturbation and no matter how much I stay with-drawled masturbation always wins... sigh.
Title: Re: The pois is over
Post by: Quantum on March 23, 2016, 09:17:58 PM
yeah I've checked your forum and hell you take alot of medications

Nas, I have chosen not to use any prescription drugs, so if you look carefully, you will see that all that I use against POIS are natural products and vitamins.  That is not what is usually meant by " taking a lot of medications", so let me politely disagree with your above comment.   Also, I do not take any of these on a daily basis - only before release, which, for me, is the less often possible.

As pointed in the post I have referred too, the lifestyle changes part is as important as the supplements, in my case.  All this put together has made a tremendous change in my life - I am not cured, but for more than a year now, I am no longer bothered at a significant level by any POIS symptom.   
Title: Re: The pois is over
Post by: Nas on March 23, 2016, 09:31:30 PM
yeah I've checked your forum and hell you take alot of medications

Nas, I have chosen not to use any prescription drugs, so if you look carefully, you will see that all that I use against POIS are natural products and vitamins.  That is not what is usually meant by " taking a lot of medications", so let me politely disagree with your above comment.   Also, I do not take any of these on a daily basis - only before release, which, for me, is the less often possible.

As pointed in the post I have referred too, the lifestyle changes part is as important as the supplements, in my case.  All this put together has made a tremendous change in my life - I am not cured, but for more than a year now, I am no longer bothered at a significant level by any POIS symptom.

yeeah sorry didn't notice they were supplements anywasy It would be hard for me to find them in my country ( Iraq ), plus I'm looking for a medication that will give me freedom to orgasm when ever I want or else it's just an eternal hell for me
such a curse
Title: Re: The pois is over
Post by: Nas on March 24, 2016, 08:18:03 AM
So as the memantine failed, I will be trying donepazil 5mg in the night to see it's effects on me psychologicaly and after orgasm to see its effects on the POIS
Title: Re: The pois is over
Post by: certainlypois2 on April 25, 2016, 04:55:09 PM
Trying pure encapsulations alpha-GPC  an advanced delivery form for phosphatidylcholine to increase acethylcholine.   It is a big help in 3 non POIS days so far.  I am in my fourth day. And day 1 after O.

I also take immunocal which is a very special whey protein which affects neurotransmitters and a powerful antioxidant. I is also a powerful lactic acid scavenger.  It  gives me lots of energy.  Can get that at amazon.com  about $80 for 30 packs (a month supply for me)

My mind is so much clearer and anxiety is almost gone with the combo.  Immunocal alone helps (taken it since 2000), but the mental clarity and peace comes from the phosphatidylcholine. Immunocal tends to increase inflammation some...

Today is day one after O.   Much, much better.  The social anxiety, concentration, inability to deal with stressful situations is almost gone!   I need to take about 3 pills a day spaced out  to keep levels up throughout the day. Still tired some, but so much better.  The feeling that the brain is on fire (I believe due to inflammation) is mostly gone.    I feel so much better and I am very optimistic about our future.  I feel the phospholipid layer in our cells  may be compromised, which limits energy production in the cells and inter cellular interactions. This may also be affecting neurological communications.

I believe that as I continue to use it everyday my body will slowly recover completely in time.  The alpha-GPC has made a phenomenal difference in just 4 days.  I buy it from www.purecaps.com.   

It is pricy, but sign up a "health practitioner" and they give a 50% discount if you sign up as such.  So it is about $20 bucks for 60 caps.
You might want to save money that way too.  Heck I practiced on my self for 23 years!  LOL

I will also try phosphatidylserine which also increases acethylcholine and see what happens.

____________

POIS and CFS sudden  simultaneous onset since 1993.


Mrraba have you tried immunopro, according to amazon reviews it is just as good. It is currently 28  dollars on amazon for 1 container and on immunopro's official website it is 50 dollars for a container.

You can  get 90day supply of alpagpc from powdercity for about 40 dollars and if you buy the powder version I believe it is cheaper.

I have a shipment coming in for me to try.
Title: Re: The pois is over
Post by: Mr Raba on April 30, 2016, 05:12:12 PM
 Again, I had bad experiences with Immunpro.  After many years of testing and trying different whey proteins, I found that immunocal is the one that works best for me. And there is a   huge difference between them on how they make feel.
Title: Re: The pois is over
Post by: certainlypois2 on May 02, 2016, 04:10:51 PM
crap, It is already here.  Immunopro does not expire for a while, I will try immunocal first and then  come back to immunopro to compare.
Title: Re: The pois is over
Post by: Mr Raba on May 02, 2016, 05:52:32 PM
Keep us posted on how you respond.  Also if u feel inflammed. Quercetin works very fast for me.
Day one great with quercetin. But i learned not to mess with day two. I Just let my body balance on its own on day 2 after O.

Please see my posts on how I take whey.  Ithink it is important not too take too much too fast.
Title: Re: The pois is over
Post by: caveeater on June 22, 2016, 05:48:41 AM
Re: olanzipine

I know someone who was on anti psychotics and had POIS symptoms, caused by the medication. After being off them for a while he has now recovered.
Title: Re: The pois is over
Post by: Nas on June 22, 2016, 01:09:21 PM
Re: olanzipine

I know someone who was on anti psychotics and had POIS symptoms, caused by the medication. After being off them for a while he has now recovered.
Can you tell us what kind of medication he was on ?
Title: Re: The pois is over
Post by: Mr Raba on September 15, 2016, 10:08:44 AM
crap, It is already here.  Immunopro does not expire for a while, I will try immunocal first and then  come back to immunopro to compare.

How did it go with immunocal?