POISCENTER

General Category => POIS Research => Topic started by: Quantum on August 03, 2021, 12:04:08 PM

Title: POIS Experiment With Tulane University Team
Post by: Quantum on August 03, 2021, 12:04:08 PM
Great News!  Dr. Caleb Natale, Urology Resident at Tulane University in New Orleans, LA, is looking for approximately five volunteers in order to do a POIS preliminary basic science experiment. He hopes that these results will guide research to find a possible pathophysiological mechanism behind POIS.

Dr. Natale has been working on POIS studies with Dr. Hellstrom and Dr. Nguyen, from the Tulane University Urology Department, and you may remember that he was involved in the POIS Survey done here with POISCenter in 2019. He is in search of willing participants who would be able to provide samples of seminal fluid for use in this experiment. His clinic is located in New Orleans, LA, so the participants could either provide samples at their facility or Dr. Natale could provide materials for participants to ship back to him if they live within the continental United States.

In this experiment, informed consent forms will be required, as well as some demographic information from the participants. Dr. Natale would also appreciate any relevant medical records that patients would be able to provide.


Dr. Natale understands that ejaculation causes POIS symptoms, but is hoping there might be some members willing to provide samples.  I told him that I was confident that we would find participants here, on POISCenter.
All interested members just have to reply here to this message, or contact in PM either me, Demografx, Limejuice, or Berlin1984, in order to receive Dr. Caleb Natale contact information, and Dr. Natale will come back to you for the continuation.

* Stay assured that if you contact us through private messaging, your application will remain confidential!


This is a great opportunity for us to help with POIS research!  I am sure we have enough members from the continental USA to find 5 participants!


Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 03, 2021, 12:38:21 PM


Great News!  Dr. Caleb Natale…is looking for approximately five volunteers in order to do a POIS preliminary basic science experiment.



Quantum:
(https://lakerschools.org/wp-content/uploads/2020/10/great-news.png)
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 03, 2021, 03:05:49 PM

Great News!  Dr. Caleb Natale…is looking for approximately five volunteers in order to do a POIS preliminary basic science experiment.


Quantum, if someone volunteers, do you know if that volunteer would be able to receive their own (private) analysis of what their own semen shows/reveals? Thanks!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 03, 2021, 08:10:38 PM

Great News!  Dr. Caleb Natale…is looking for approximately five volunteers in order to do a POIS preliminary basic science experiment.



Quantum, if someone volunteers, do you know if that volunteer would be able to receive their own (private) analysis of what their own semen shows/reveals? Thanks!
Good question.  I would think so but should be confirmed with Dr.Natale.
I am sure that those who will apply will have the opportunity to receive answers to their questions from Dr.Natale.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 04, 2021, 01:00:46 AM

Great News!  Dr. Caleb Natale, Tulane University…is looking for approximately five volunteers in order to do a POIS preliminary basic science experiment.



Quantum, if someone volunteers, do you know if that volunteer would be able to receive their own (private) analysis of what their own semen shows/reveals? Thanks!
Good question.  I would think so but should be confirmed with Dr.Natale.
I am sure that those who will apply will have the opportunity to receive answers to their questions from Dr.Natale.




Hi, Quantum!

Congratulations again! Since this forum began (in 2007), I’ve been waiting for this: a plethora of POIS Research!

If you need a 5th Tulane volunteer, count me in!

But I’d prefer a *younger* POISer to be the 5th volunteer (I’m 75 and
not-all-that-representative-of-the-POISer-population that I’ve seen here in all my 14 years at this forum :) )

Also, in the meantime, Quantum,  if you can please kindly get an answer from Dr. Natale for me (you know him, I don’t) to my above question, that would be great.

Many thanks!
Demo
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 04, 2021, 08:35:30 AM

Hi, Quantum!

Congratulations again! Since 2007, I’ve been waiting for this: a plethora of POIS Research!

If you need a 5th Tulane volunteer, count me in!

But I’d prefer a *younger* POISer to be the 5th volunteer (I’m 75 and
not-all-that-representative-of-the-POISer-population that I’ve seen here in all my 14 years at this forum :) )

Also, in the meantime, Quantum,  if you can please kindly get an answer from Dr. Natale for me (you know him, I don’t) to my above question, that would be great.

Many thanks!
Demo


I have sent your question to Dr.Natale, and will give you his answer as soon as received.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 04, 2021, 08:37:24 AM

I have sent your question to Dr.Natale, and will give you his answer as soon as received.


Quantum, thank you very much!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 04, 2021, 10:29:35 AM

I have sent your question to Dr.Natale, and will give you his answer as soon as received.


Quantum, thank you very much!
Demo, here is Dr.Natale's answer to your question:
"I would not mind sharing the results with him. However, I am looking for some specific markers of immune response, not completing a full semen analysis. I am actually more concerned with the environment surrounding the semen than the actual semen itself.   Thanks"
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 04, 2021, 10:30:42 AM

I have sent your question to Dr.Natale, and will give you his answer as soon as received.


Quantum, thank you very much!
Demo, here is Dr.Natale's answer to your question:
"I would not mind sharing the results with him. However, I am looking for some specific markers of immune response, not completing a full semen analysis. I am actually more concerned with the environment surrounding the semen than the actual semen itself.   Thanks"

Wonderful, Quantum.

Thanks again!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: VSmasher on August 04, 2021, 07:54:15 PM
I'm in
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 04, 2021, 08:41:57 PM
I'm in
Great!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 04, 2021, 09:24:41 PM
I'm in
Great, VSmasher, I have just sent you the contact information.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: berlin1984 on August 05, 2021, 02:39:18 AM
Maybe someone could post it to Reddit.
Muon?

https://www.reddit.com/r/POIS/
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: commander_meh on August 05, 2021, 09:14:50 PM
I?d be willing to sign up too if they need another volunteer
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 05, 2021, 09:25:22 PM
I?d be willing to sign up too if they need another volunteer

Great!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 06, 2021, 11:18:20 AM
I?d be willing to sign up too if they need another volunteer
Yes, commander, I am sending you the contact info in PM right away.  Thanks for your involvement!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: rollercoaster on August 10, 2021, 09:10:39 AM
You can count me in, I'm in TX. I am south Asian male in my early 30's.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 10, 2021, 10:35:15 AM
You can count me in, I'm in TX. I am south Asian male in my early 30's.
Great, rollercoaster!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 10, 2021, 08:57:20 PM
You can count me in, I'm in TX. I am south Asian male in my early 30's.
Information sent, rollercoaster, thanks for your involvement!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Spartak on August 18, 2021, 04:47:03 AM
Great news indeed!
Best of luck, if I lived cin US I would participate as well :)
Hope there would be some study in Europe one say :)
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 18, 2021, 07:35:31 AM
Dr Natale would like a few more applications. 

Any other members interested ? 


Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Samir on August 18, 2021, 02:15:24 PM
Dr Natale would like a few more applications. 

Any other members interested ? 
Most definitely interested!!  I was qualified for the Los Angeles study but then covid hit.  I would love to contribute to the research.  Please contact me asap!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 18, 2021, 02:21:50 PM
Dr Natale would like a few more applications. 

Any other members interested ? 
Most definitely interested!!  I was qualified for the Los Angeles study but then covid hit.  I would love to contribute to the research.  Please contact me asap!
Sure, Samir, I am sending you the information by private message.

Thanks for your involvement

Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Samir on August 18, 2021, 03:54:22 PM
Sure, Samir, I am sending you the information by private message.

Thanks for your involvement


Thank you for making this happen!  I've replied to your PM. :)
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Roland Rock on August 19, 2021, 08:40:41 AM
Interested.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 19, 2021, 08:43:43 AM
Interested.
Great, I am sending you the information in a private message.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 19, 2021, 10:06:36 AM
Interested.
Great, I am sending you the information in a private message.
Roland Rock,
Nice to know!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Exanuage on August 24, 2021, 04:18:25 PM
If you still need more volunteers, I would be more than happy to participate.
I'm a 25 YO married, Middle Eastern man. I live in Arizona.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 24, 2021, 07:06:26 PM
If you still need more volunteers, I would be more than happy to participate.
I'm a 25 YO married, Middle Eastern man. I live in Arizona.
Thank you, Exanuage!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 24, 2021, 09:42:30 PM
If you still need more volunteers, I would be more than happy to participate.
I'm a 25 YO married, Middle Eastern man. I live in Arizona.
Great ! I have just sent you the contact information for Dr.Natale, look in your private messages.
Thank you for your involvement !
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Clues on August 25, 2021, 01:41:38 AM
Thank you to all our US friends who are volunteering for this. :)
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 25, 2021, 05:42:57 AM
Thank you to all our US friends who are volunteering for this. :)
Thank you, Clues!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: ThatOneGuy2 on August 26, 2021, 12:44:41 AM
I would be interested in applying.  I am 35 and in Los Angeles.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Poldimax on August 26, 2021, 03:16:40 AM
I am interested, i am 32 i have POIS since puberty. Live in Sacramento, California
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 26, 2021, 10:40:35 AM

I would be interested in applying.  I am 35 and in Los Angeles.


I am interested, i am 32 i have POIS since puberty. Live in Sacramento, California


Teriffic, ThatOneGuy2 & Poldimax!!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 26, 2021, 11:18:56 AM

I would be interested in applying.  I am 35 and in Los Angeles.


I am interested, i am 32 i have POIS since puberty. Live in Sacramento, California



Teriffic, ThatOneGuy2 & Poldimax!!
Ok, I sent contact information in PM to both of you, thank you !
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Mr Raba on August 29, 2021, 10:18:22 PM
Interested. 30 years with POIS.
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: demografx on August 29, 2021, 10:25:40 PM

Interested. 30 years with POIS.


Great to hear, Mr Raba!
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on August 30, 2021, 07:29:55 AM
Interested. 30 years with POIS.
I have just sent you a PM with Dr.Natale's contact information :) 
Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: ozmoses on August 30, 2021, 06:44:51 PM
This is great.  I did contact Dr. Natale with some of my own discoveries/testing/diagnoses/treatment which have resulted in me feeling 80% better.  See below w/ test results/attachments:

<<<<Hello Dr. Natale,

I heard about your research on one of the POIS forums. I'm sure you're inundated, so let me be quick. 

I have had these POIS symptoms for the past 30+ years, but worst over the past 7.  (Irritability, excessive urination, excessive sweating, complete social withdrawal, anhedonia, dark circles under eyes, skin hyperpigmentation (black stuff coming out of skin in shower/bath-mostly post orgasm).   At it's worst, I'd sleep at least 12 hours after orgasm.     

I am certain that there is a low acetylcholinesterase component which can lead to cholinergic crisis (post orgasm) as well as failure to break down acetylcholine (a problem in high protein diets) and organophosphate buildup.  I have test results to show this).  Additionally, low aldosterone/renin levels (adrenal insufficiency)  low 4 point cortisol saliva test, at least in my case, is also a contributing factor.   Gastric testing shows high H Pylori, streptococcus and enteroccocus levels  and potentially low stomach acid.  Hypothyroidism as well.  I would recommend including this in your research.  I did a semen allergy test (blood test) and it came back negative, but perhaps it could be an intolerance. Haven't tested for that yet.  High levels of mycotoxins (urine testing has appeared as well).  Reactivated Epstein Barr Virus "may" also be relevant. 

I am doing much better with treatment (Adderall is essential) and am convinced that there are some overlapping conditions that most of us POIS sufferers share that can be treated.  I believe that the GI Map test should be done by all of us.  Adrenal testing and stomach acid testing as well. 

Nootropics like piracetam and centrophenoxine have been super helpful as well as alpha lipoic acid. I still take robinul/ditropan in moderation.   I'm 80% better than I was 7 years ago when I was nearing autism spectrum type of behavior (always feeling toxic).   I hope that this is helpful.  There are some HUGE discoveries here.  Most of these tests can be ordered directly using sites like ultalabtests.com, walkinlab.com, requestatest.com etc.  For the GI Map (Diagnostic Solutions), I needed my doctor to order.



Title: Re: Volunteers From USA Needed for a POIS Experiment With Tulane University Team
Post by: Quantum on September 01, 2021, 12:12:03 PM
Thanks, everyone, Dr.Natale now has enough applications for his small trial !
I am glad to see that we are motivated to help POIS research.  Stay tuned, as soon as other POIS research projects will need volunteers, you will be notified !
We will also communicate you any results regarding this experiment as soon as we will receive them, whatever they are. 



Title: Re: POIS Experiment With Tulane University Team
Post by: Prospero on October 11, 2021, 04:01:08 PM
As I have discovered recently that my semen contains an overgrowth of the bacteria Streptococcus anginosus, I wonder if Dr. Natale will realize a bacterial analysis of the seminal fluid of the volunteers. I suspect that not many of us have done such an analysis, maybe there would be interesting results.
Title: Re: POIS Experiment With Tulane University Team
Post by: Disaster on March 09, 2022, 06:30:57 PM
As I have discovered recently that my semen contains an overgrowth of the bacteria Streptococcus anginosus, I wonder if Dr. Natale will realize a bacterial analysis of the seminal fluid of the volunteers. I suspect that not many of us have done such an analysis, maybe there would be interesting results.

They do that for prostatitis which is not like POIS
Title: Re: POIS Experiment With Tulane University Team
Post by: Copperred on January 03, 2023, 04:00:44 PM
Hello -- has there been an update from Dr. Natale on his study?  Did he collect all the samples and run the test/experiments he planned?  Any indication of him releasing any findings?   Thank you.
Title: Re: POIS Experiment With Tulane University Team
Post by: Quantum on January 03, 2023, 09:25:26 PM
Hello -- has there been an update from Dr. Natale on his study?  Did he collect all the samples and run the test/experiments he planned?  Any indication of him releasing any findings?   Thank you.
Hi Copperred,
Thanks for asking!  I did not receive any feedback since then.  After reading your post, I have sent an email to Dr.Natale, hoping to receive an update about this project.
I will sure share any news I get from Dr.Natale.
Title: Re: POIS Experiment With Tulane University Team
Post by: demografx on January 03, 2023, 10:13:29 PM

Hello -- has there been an update from Dr. Natale on his study?  Did he collect all the samples and run the test/experiments he planned?  Any indication of him releasing any findings?   Thank you.


Hi Copperred,
Thanks for asking!  I did not receive any feedback since then.  After reading your post, I have sent an email to Dr.Natale, hoping to receive an update about this project.
I will sure share any news I get from Dr.Natale.


Thanks, I am very interested as well.
Title: Re: POIS Experiment With Tulane University Team
Post by: Muon on July 13, 2024, 03:41:50 PM
Update?
Hello -- has there been an update from Dr. Natale on his study?  Did he collect all the samples and run the test/experiments he planned?  Any indication of him releasing any findings?   Thank you.
Title: Re: POIS Experiment With Tulane University Team
Post by: Quantum on July 13, 2024, 05:13:07 PM
Update?
Hello -- has there been an update from Dr. Natale on his study?  Did he collect all the samples and run the test/experiments he planned?  Any indication of him releasing any findings?   Thank you.
All of my contact attempts to get some feedback were left unanswered.
Feel free to try yourself.