POISCENTER
POIS Cause/Treatment Discussions => General Alternative Causes and Treatments of POIS => Topic started by: Labyrinth on October 22, 2019, 07:36:34 AM
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Hello every one
I suffer from chronic sensitivity to many drugs which is driving me crazy
Am not able to tolerate cns drugs
Mood stabiliser. Low dose antipsych
Antidepressants
All gave me strange reaction
Any one here same. Am feeling exhausted and overwhelmed
I only do O once every 6 days and have also multiple food allergies. Hope that make sense to any one of you
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Yeah I'm also sensitive to a lot pharmaceutical drugs also and I have no idea why. A lot of them can give me brain fog or pain
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Yes the food sensitivities are driving me nuts. It's probably a failure of immune tolerance driven by Tregs/Bregs. Gut Tregs could communicate to distant mucosal surfaces. Mast cells could be instable as well, as in, mast cell activation syndrome. I did react to citalopram's lowest dose giving me pain in center of my head and had an extreme reaction to Daktarin oral gel.
Use the search bar on the main page to look for more info about mast cell and sensitivity related threads.
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Did some body found kinda of solution for this
It does not make any sense for me
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Try to block MRGPRX2 https://en.wikipedia.org/wiki/MRGPRX2
Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions (https://www.frontiersin.org/articles/10.3389/fimmu.2018.03027/full)
Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions (https://www.nature.com/articles/nature14022?fbclid=IwAR2tPjPfYoc9Ysg8jMRiuLL_Tm5yT_aNqoG-OW7y-D8zC4LpcQcLI0HQxXM)