POISCENTER
General Category => Articles, References and Links => Topic started by: b_jim on July 28, 2014, 03:16:51 PM
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I finally found a scientific document to explain CLEARLY how does the hot flashes work.
It's very interesting. PDF File In french, Bouffees de chaleur et traitement hormonal du cancer de la prostate (http://www.google.fr/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&cad=rja&uact=8&ved=0CCgQFjAB&url=http%3A%2F%2Fwww.anamacap.fr%2Ftelechargement%2Fbouffees-de-chaleur.pdf&ei=QanWU9erGoHO0QWIgIGIDQ&usg=AFQjCNFQC0dZdmZ1VlsnjMgdVkBEMpk_Qw&bvm=bv.71778758,d.d2k)
Very simply, 3 points :
- The cause of hot flashes is the increased levels of catecholamine in hypothalamus, center of temp regulation. The main catecholamine is noradrenaline.
- Opiod peptides down-regulate (=decrease ) level of these catecholamines then decrease hot flashes.
- Steroid hormones (Testosterone, DHT, oestrogens/progesterone) up-regulates (=increase) the levels of opiod peptides.
With these element you may understand a lot of things in Pois.
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Hot flashes : link hormones to hypothalamic cells : KNDy cells
In french :
http://www.lequotidiendumedecin.fr/actualites/article/2012/12/12/candy-au-pays-des-bouffees-de-chaleur_631797
I think I have a better knowledge of this and maybe, I hope, a batter knowledge to understand Pois :
I said in the first post that hypothalamus is the center of thermo-regulation.
But inside hypothalamus, there is a particular kind of cells called : KNDy cells.
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Cela étant dit, les bouffées de chaleur, comme celles survenant à la ménopause (mais aussi chez les hommes sous traitement anti-androgène) constituent une énigme.
Hotflashes during women menopause (but during anti-androgen meds for men) are still mysterious.
=> Low testosterone = hot flashes
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Very simply, 3 points :
- The cause of hot flashes is the increased levels of catecholamine in hypothalamus, center of temp regulation. The main catecholamine is noradrenaline.
- Opiod peptides down-regulate (=decrease ) level of these catecholamines then decrease hot flashes.
- Steroid hormones (Testosterone, DHT, oestrogens/progesterone) up-regulates (=increase) the levels of opiod peptides.
With these element you may understand a lot of things in Pois.
Very interesting topic B_Jim. I am very interested in the hypothalamus in connection with POIS. So if you take testosterone does that mean that you will get less hot flashes and reduce the POIS?
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There is a supplement marketed for women in menopause that claims to reduce hot flashes by 90%..
It's made from some kind of pollen and called "Serelys".
Maybe makes sense to check if it can somehow be useful to us.
(by "us" I mean male POISers, but input by female POISers is appreciated too)
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Bumping an older thread because in my research I've found that low T can be a cause of hot flashes. But clinically it has only been common in androgen deprivation therapy, a treatment for prostate cancer that restricts testosterone production.
Good reading:
https://www.health.harvard.edu/mens-health/hot-flashes-in-men-an-update
Clinic I'm thinking about reaching out to about POIS:
https://rosewellness.com/hot-flashes-in-men/
After years of POIS, the last year or two I've started to get hot flashes. At first I thought I was crazy, but with all the posts on it here, I think it's something a lot of you have already had. I do have to note that most of the time I get them when I'm off my regiment and in POIS.