Author Topic: Xanthiol Nicotinate - Benefits, Risks and Function in POIS  (Read 135332 times)

victor.kons

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #15 on: July 10, 2011, 04:01:34 AM »
I have a reply to my shout "who tried XN". I will translate these replies and post them here.

One person "gabin" writes that he tried niacin acid in pills in doses 200-250mg at a time, it didn't have any effect on POIS symptoms for him, he writes that he didn't tried injections.

Victor
« Last Edit: July 10, 2011, 07:16:45 AM by victor.kons »
3 day POIS sessions, brain fog, heartbeat, digestion problems. Currently using XN for 95% relief from POIS symptoms.

Starsky

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #16 on: July 10, 2011, 04:34:12 AM »
Is Niacin a compound of semen?

Starsky

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #17 on: July 10, 2011, 04:35:50 AM »
"Fenugreek contains high concentrations of choline, tryptophan, ascorbic acid, niacin and potassium."

Bulls eye

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #18 on: July 10, 2011, 04:59:16 AM »
Hello victor , my symptoms are very much like yours , am currently 23 ,my symptoms started at my first onset of puberty and was strictly cognitive at that time , it was devastating for me because my IQ was my only asset at school , i'm very happy for you that you found stability and knew how to control pois , wish you all the best :)

I'm having trouble finding XN injections where I live , but there is ceberolysin trade name is cerebrolysin , did it work for you ?

victor.kons

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #19 on: July 10, 2011, 07:14:35 AM »
Hi Bulls eye,
Hello victor , my symptoms are very much like yours , am currently 23 ,my symptoms started at my first onset of puberty and was strictly cognitive at that time , it was devastating for me because my IQ was my only asset at school , i'm very happy for you that you found stability and knew how to control pois , wish you all the best :)

I'm having trouble finding XN injections where I live , but there is ceberolysin trade name is cerebrolysin , did it work for you ?
No, cerebrolysin didn't help with POIS for me at all

Victor
3 day POIS sessions, brain fog, heartbeat, digestion problems. Currently using XN for 95% relief from POIS symptoms.

Ccconfucius

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #20 on: July 10, 2011, 08:30:32 AM »
"Fenugreek contains high concentrations of choline, tryptophan, ascorbic acid, niacin and potassium."
Guess what is also a mild vasodilator garlic

demografx

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #21 on: July 10, 2011, 11:43:14 AM »
" Niacin Physiology:

Niacin is important for the synthesis of the sex and adrenal hormones. Its primary sexual affect is from the side effect of the vitamin. Briefly after ingestion, niacin can produce sensations of intense warmth that quickly spreads throughout the body. This effect, is secondary to a release of histamine that produces a dilation of blood vessels and capillaries which results in subsequent increase in blood flow. The vasodilatation of the blood vessel is very similar to the flush felt instantaneously during sexual excitement and orgasms. The pleasurable feeling can last up to 20 minutes and because there is a larger than normal histamine release, the feeling is often more dramatic than the sensations that occur during intercourse. "

mod edit - bold-emphasis above is mine, demo

From http://www.physiciansselect.co.uk/niacin-vitamin-b3-information.htm
« Last Edit: July 10, 2011, 11:32:50 PM by demografx »
Usually have major POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks associated with it.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business.

demografx

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #22 on: July 10, 2011, 11:46:06 AM »
Holy Moly! After re-reading POIS-SUFFERER's post above, it suddenly hit me: my POIS has strangely but dramatically improved recently - 90% to 100% POIS relief, over my usual 80% relief with testosterone replacement therapy (TRT)...

At the same time, I also was recently put on NIASPANĀ® (niacin extended-release tablets) for my cholesterol!

I hope this is real and not just a happy interlude!

Stay tuned!

Wow.

This is NOT a recommendation for you to try it, though I really hope this helps the forum's research! And - as always - work closely with your physician, and keep in mind that we are all different! What works for one person might not work for someone else. And could even be harmful.


Demo, I like to think that this is the B3 which helps, this would made things easy for many of you, because you don't have XN easily available, but I can't be sure until someone really tries niacin and XN and says that they have the same positive effect for him...

Victor


I agree! Thank you Victor for your confirming comment!
Usually have major POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks associated with it.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business.

Habibou

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #23 on: July 10, 2011, 12:20:43 PM »
Very interesting Demo, it seems to be a central finding !  thank you It seems to explain a lot more, and sounds very familiar for me at least.. The pois episode, intense long lasting warmth through the whole body, sweating. I noticed I ask everybody if the room is warm for them, just to check if I am not an exception there.

french article translated" niacin is a main factor in the sexual hormones production, blood stream, energy production AND histamine release"

"Some people cant support very well histamine release/absorption and it implies : Headaches, skin troubles, heart palpitations, dizziness, intense warmth feeling, digestive troubles (nausea, colon disorders, stomach.
The symptoms disappear alone in some hours after the histamine absorption."

Histamine could explain the "fake allergic reaction feeling" and the huge amount of it could explain why a simply "antihistamine" never worked for us.
Perhaps the Niacin by injections could prevent the wrong reaction by regulating the Histamine release during arousal and the O.

It would be good to have medical view on this Niacin findings and the possible link with our POIS. I hope Dr Waldinger would have a look on it !
Brain fog 90%  + tired all the time ,sport intolerance, fast heartbeat, colon inflammation

Starsky

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #24 on: July 10, 2011, 12:41:02 PM »
Common herbs with vasodilatory actions:
? Achillea millefolium (Yarrow)
? Allium sativum (Garlic)
? Amoracia rusticana (Horseradish)
? Berberis vulgaris (Barberry)
? Cimicifuga racemosa(Black cohosh)
? Coleus forskholii (Coleus)
? Coptis spp. (Goldenthread)
? Crataegusspp. (Hawthorn)
? Eleutherococcus senticosus(Siberian ginseng)
? Ginkgo biloba(Ginkgo)
? Melissa offiicnalis (Lemon Balm)
? Olea europaea (Olive leaf)
? Panax ginseng(Chinese Ginseng)
? Petroselinum crispum (Parsley)
? Scutellaria baicalensis (Baical Skullcap)
? Tilia europaea (Linden Flower)
? Trigonella foenum-graecum (Fenugreek)
? Urtica dioica (Nettles)
? Valeriana officinalis(Valerian)
? Viburnum spp. (Cramp, Bark, Black Haw)
? Veratrum viride (American Hellebore)
? Verbena officinalis (Vervain)
? Xanthoxylum americanum (Prickly Ash)
? Zingiber officinale(Ginger)

demografx

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #25 on: July 10, 2011, 01:50:56 PM »



It would be good to have a medical view on this Niacin finding and the possible link with our POIS.


Habibou, I agree wholeheartedly.

And our POIS-NORD Research Fund is the fastest way to find out!
http://poiscenter.com/forums/index.php?topic=125.0


Usually have major POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks associated with it.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business.

Habibou

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #26 on: July 10, 2011, 07:20:02 PM »
I tried to give my donation but my "card doesn't work on international websites"  >:( I will send it with another card soon so ! But you are right, we really all need to take part of it at our own scale  :) each $ is welcome !
« Last Edit: July 10, 2011, 07:23:24 PM by Habibou »
Brain fog 90%  + tired all the time ,sport intolerance, fast heartbeat, colon inflammation

demografx

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #27 on: July 10, 2011, 11:00:00 PM »
Niacin monitoring -

Today (POIS onset) was 90%+ POIS-free. After my dose of 500mg (daily) NIASPAN, it feels like it jumped to 100%.

Placebo effect? Time will tell.

(Keep in mind that TRT is still my main POIS "cure", with 2.5 years proven 80% efficacy).
« Last Edit: July 10, 2011, 11:23:43 PM by demografx »
Usually have major POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks associated with it.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business.

victor.kons

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #28 on: July 11, 2011, 05:36:32 AM »
Niacin monitoring -

Today (POIS onset) was 90%+ POIS-free. After my dose of 500mg (daily) NIASPAN, it feels like it jumped to 100%.

Placebo effect? Time will tell.

(Keep in mind that TRT is still my main POIS "cure", with 2.5 years proven 80% efficacy).
Thats interesting.

I can say that:
1. I'm taking XN starting from February 2010, and through all this time it simply works, so probably its not a placebo.
2. I have not experimented of taking XN too much, when I have the POIS, but I noticed that when in POIS it has far less effect, e.g. you need to take very high dose to feel the relief. But again, I didn't experimented much with it. Your dose of 500mg looks big enough, thats why you might feel the relief of up to 20% to your TRT, but I wonder how much niacin in this dose?

Victor

3 day POIS sessions, brain fog, heartbeat, digestion problems. Currently using XN for 95% relief from POIS symptoms.

Daveman

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Re: Xanthiol Nicotinate - Benefits, Risks and Function in POIS
« Reply #29 on: July 11, 2011, 09:15:26 AM »

1. I'm taking XN starting from February 2010, and through all this time it simply works, so probably its not a placebo.
2. I have not experimented of taking XN too much, when I have the POIS, but I noticed that when in POIS it has far less effect, e.g. you need to take very high dose to feel the relief. But again, I didn't experimented much with it. Your dose of 500mg looks big enough, thats why you might feel the relief of up to 20% to your TRT, but I wonder how much niacin in this dose?

Victor



In point 2 are you refering to when you had forgotten to take XN before so as to prevent POIS? The question is related to point 1. If XN stops your POIS, you wouldn't have POIS to try the XN.

I guess what you mean is that taking it too late (i.e. after the orgasm) it doesn't work much.

I assume you don't take XN daily either right? Just when you know you are going to have an orgasm.

WITHOUT RESEARCH THERE WILL BE NO CURE!
Sessions 5 to 9 days, mostly Flu-like, joints, digestion problems, light cognitive.
Niacin has changed my lif though, now 1 day MAX.
Somewhere in this interaction with Niacin is the answer!